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A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
Cytochrome P450 2E1 (CYP2E1) is a key target protein in the development of alcoholic and nonalcoholic fatty liver disease (FLD). The pathophysiological correlate is the massive production of reactive oxygen species. The role of CYP2E1 in the development of hepatocellular carcinoma (HCC), the final c...
Autores principales: | Diesinger, Torsten, Lautwein, Alfred, Bergler, Sebastian, Buckert, Dominik, Renz, Christian, Dvorsky, Radovan, Buko, Vyacheslav, Kirko, Siarhei, Schneider, Edith, Kuchenbauer, Florian, Kumar, Mukesh, Günes, Cagatay, Genze, Felicitas, Büchele, Berthold, Simmet, Thomas, Haslbeck, Martin, Masur, Kai, Barth, Thomas, Müller-Enoch, Dieter, Wirth, Thomas, Haehner, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872744/ https://www.ncbi.nlm.nih.gov/pubmed/33604316 http://dx.doi.org/10.1155/2021/8854432 |
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