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Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependent

PURPOSE: d,l-methadone (MET), an analgesic drug used for pain treatment and opiate addiction, has achieved attention from oncologists and social media as possible chemoensitizing agent in cancer therapy, notably brain cancer (glioblastoma multiforme, GBM). MET has been reported to enhance doxorubici...

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Detalles Bibliográficos
Autores principales: Haas, Bodo, Ciftcioglu, Janine, Jermar, Sanja, Weickhardt, Sandra, Eckstein, Niels, Kaina, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872955/
https://www.ncbi.nlm.nih.gov/pubmed/33315125
http://dx.doi.org/10.1007/s00432-020-03485-3