Cargando…

Selective endocytosis of recombinant human BMPs through cell surface heparan sulfate proteoglycans in CHO cells: BMP-2 and BMP-7

Cell surface heparan sulfate proteoglycan (HSPG)-mediated endocytosis results in poor yields of recombinant human bone morphogenetic proteins (rhBMPs) from CHO cell cultures. Upon incubation of rhBMP-2 and rhBMP-7 with CHO cells at 37 °C, both rhBMP-2 and rhBMP-7 bound to the cell surface HSPGs in C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Mi Gyeom, Kim, Che Lin, Kim, Young Sik, Jang, Ju Woong, Lee, Gyun Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873082/ https://www.ncbi.nlm.nih.gov/pubmed/33564092 http://dx.doi.org/10.1038/s41598-021-82955-1

Ejemplares similares

Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction
por: Pegge, James, et al.
Publicado: (2020)

A Targeted Glycan-Related Gene Screen Reveals Heparan Sulfate Proteoglycan Sulfation Regulates WNT and BMP Trans-Synaptic Signaling
por: Dani, Neil, et al.
Publicado: (2012)

Heparan Sulfate Deficiency in Cartilage: Enhanced BMP-Sensitivity, Proteoglycan Production and an Anti-Apoptotic Expression Signature after Loading
por: Gerstner, Matthias, et al.
Publicado: (2021)

Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression
por: Nagarajan, Arvindhan, et al.
Publicado: (2018)

Heparan sulfate proteoglycans and cancer
por: Blackhall, F H, et al.
Publicado: (2001)

Heparan Sulfate Proteoglycans in Infection
por: Bartlett, Allison H., et al.
Publicado: (2011)

Heparan Sulfate Proteoglycans in Tauopathy
por: Zhu, Yanan, et al.
Publicado: (2022)

Endocytosis and Trafficking of Heparan Sulfate Proteoglycans in Triple-Negative Breast Cancer Cells Unraveled with a Polycationic Peptide
por: Mandarini, Elisabetta, et al.
Publicado: (2020)

Two Modulators of Skeletal Development: BMPs and Proteoglycans
por: Koosha, Elham, et al.
Publicado: (2022)

Combinatorial Roles of Heparan Sulfate Proteoglycans and Heparan Sulfates in Caenorhabditis elegans Neural Development
por: Kinnunen, Tarja K.
Publicado: (2014)

Heparan Sulfate Proteoglycans in Human Colorectal Cancer
por: Vicente, Carolina Meloni, et al.
Publicado: (2018)

Profiling Heparan Sulfate Proteoglycans in Ovarian Carcinoma
por: Clamp, Andrew R., et al.
Publicado: (2005)

Heparan sulfate proteoglycans regulate autophagy in Drosophila
por: Reynolds-Peterson, Claire E., et al.
Publicado: (2017)

Heparan Sulfate Proteoglycan Signaling in Tumor Microenvironment
por: De Pasquale, Valeria, et al.
Publicado: (2020)

Heparan Sulfate Proteoglycans: Key Mediators of Stem Cell Function
por: Ravikumar, Maanasa, et al.
Publicado: (2020)

Importance of Heparan Sulfate Proteoglycans in Pancreatic Islets and β-Cells
por: Takahashi, Iwao
Publicado: (2022)

Acute UV Irradiation Increases Heparan Sulfate Proteoglycan Levels in Human Skin
por: Jung, Ji-Yong, et al.
Publicado: (2012)

Heparan sulfate proteoglycans (HSPGs) and chondroitin sulfate proteoglycans (CSPGs) function as endocytic receptors for an internalizing anti-nucleic acid antibody
por: Park, Hyunjoon, et al.
Publicado: (2017)

Perlecan domain 1 recombinant proteoglycan augments BMP-2 activity and osteogenesis
por: DeCarlo, Arthur A, et al.
Publicado: (2012)

Heparan Sulfate Proteoglycans as Emerging Players in Synaptic Specificity
por: Condomitti, Giuseppe, et al.
Publicado: (2018)

Heparan Sulfate Proteoglycan Clustering in Wnt Signaling and Dispersal
por: Mii, Yusuke, et al.
Publicado: (2020)

An Atlas of Heparan Sulfate Proteoglycans in the Postnatal Rat Lens
por: Wishart, Tayler F. L., et al.
Publicado: (2021)

Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer
por: Furini, Simone, et al.
Publicado: (2021)

Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans
Publicado: (1992)

Identification of a lipid-anchored heparan sulfate proteoglycan in Schwann cells
Publicado: (1990)

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity
por: Brunetti, Jlenia, et al.
Publicado: (2019)

Heparan Sulfate Proteoglycans as Attachment Factor for SARS-CoV-2
por: Liu, Lin, et al.
Publicado: (2021)

Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation
por: Ho, Andrew M, et al.
Publicado: (2008)

Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs)
por: Rauch, Jennifer N., et al.
Publicado: (2018)

Alterations in heparan sulfate proteoglycan synthesis and sulfation and the impact on vascular endothelial function
por: Pretorius, Danielle, et al.
Publicado: (2022)

Synthesis by Schwann cells of basal lamina and membrane-associated heparan sulfate proteoglycans
Publicado: (1985)

Cell surface heparan sulfate proteoglycans contribute to intracellular lipid accumulation in adipocytes
por: Wilsie, Larissa C, et al.
Publicado: (2005)

Inhibition of SARS Pseudovirus Cell Entry by Lactoferrin Binding to Heparan Sulfate Proteoglycans
por: Lang, Jianshe, et al.
Publicado: (2011)

Mapping the Interactome of the Nuclear Heparan Sulfate Proteoglycan Syndecan-1 in Mesothelioma Cells
por: Kumar-Singh, Ashish, et al.
Publicado: (2020)

Towards Understanding the Roles of Heparan Sulfate Proteoglycans in Alzheimer's Disease
por: Zhang, Gan-lin, et al.
Publicado: (2014)

Heparan sulfate proteoglycans: a sugar code for vertebrate development?
por: Poulain, Fabienne E., et al.
Publicado: (2015)

Heparan sulfate proteoglycans present PCSK9 to the LDL receptor
por: Gustafsen, Camilla, et al.
Publicado: (2017)

Membrane anchoring of heparan sulfate proteoglycans by phosphatidylinositol and kinetics of synthesis of peripheral and detergent-solubilized proteoglycans in Schwann cells
Publicado: (1989)

Heparanase Facilitates Cell Adhesion and Spreading by Clustering of Cell Surface Heparan Sulfate Proteoglycans
por: Levy-Adam, Flonia, et al.
Publicado: (2008)

Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells
por: Lim, Hooi Ching, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_j835ncalghmmre05n90uh3t51n