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The secreted inhibitor of invasive cell growth CREG1 is negatively regulated by cathepsin proteases

Previous clinical and experimental evidence strongly supports a breast cancer-promoting function of the lysosomal protease cathepsin B. However, the cathepsin B-dependent molecular pathways are not completely understood. Here, we studied the cathepsin-mediated secretome changes in the context of the...

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Detalles Bibliográficos
Autores principales: Gomez-Auli, Alejandro, Hillebrand, Larissa Elisabeth, Christen, Daniel, Günther, Sira Carolin, Biniossek, Martin Lothar, Peters, Christoph, Schilling, Oliver, Reinheckel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873128/
https://www.ncbi.nlm.nih.gov/pubmed/32385587
http://dx.doi.org/10.1007/s00018-020-03528-5