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Novel urinary glycan profiling by lectin array serves as the biomarkers for predicting renal prognosis in patients with IgA nephropathy

In IgA nephropathy (IgAN), IgA1 molecules are characterized by galactose deficiency in O-glycans. Here, we investigated the association between urinary glycosylation profile measured by 45 lectins at baseline and renal prognosis in 142 patients with IgAN. The primary outcome was estimated glomerular...

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Detalles Bibliográficos
Autores principales: Kawakita, Chieko, Mise, Koki, Onishi, Yasuhiro, Sugiyama, Hitoshi, Yoshida, Michihiro, Yamada, Masao, Wada, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873239/
https://www.ncbi.nlm.nih.gov/pubmed/33564009
http://dx.doi.org/10.1038/s41598-020-77736-1