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L1 retrotransposons exploit RNA m(6)A modification as an evolutionary driving force

L1 retrotransposons can pose a threat to genome integrity. The host has evolved to restrict L1 replication. However, mechanisms underlying L1 propagation out of the host surveillance remains unclear. Here, we propose an evolutionary survival strategy of L1, which exploits RNA m(6)A modification. We...

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Detalles Bibliográficos
Autores principales: Hwang, Sung-Yeon, Jung, Hyunchul, Mun, Seyoung, Lee, Sungwon, Park, Kiwon, Baek, S. Chan, Moon, Hyungseok C., Kim, Hyewon, Kim, Baekgyu, Choi, Yongkuk, Go, Young-Hyun, Tang, Wanxiangfu, Choi, Jongsu, Choi, Jung Kyoon, Cha, Hyuk-Jin, Park, Hye Yoon, Liang, Ping, Kim, V. Narry, Han, Kyudong, Ahn, Kwangseog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873242/
https://www.ncbi.nlm.nih.gov/pubmed/33563981
http://dx.doi.org/10.1038/s41467-021-21197-1