Cargando…

L1 retrotransposons exploit RNA m(6)A modification as an evolutionary driving force

L1 retrotransposons can pose a threat to genome integrity. The host has evolved to restrict L1 replication. However, mechanisms underlying L1 propagation out of the host surveillance remains unclear. Here, we propose an evolutionary survival strategy of L1, which exploits RNA m(6)A modification. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hwang, Sung-Yeon, Jung, Hyunchul, Mun, Seyoung, Lee, Sungwon, Park, Kiwon, Baek, S. Chan, Moon, Hyungseok C., Kim, Hyewon, Kim, Baekgyu, Choi, Yongkuk, Go, Young-Hyun, Tang, Wanxiangfu, Choi, Jongsu, Choi, Jung Kyoon, Cha, Hyuk-Jin, Park, Hye Yoon, Liang, Ping, Kim, V. Narry, Han, Kyudong, Ahn, Kwangseog
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873242/ https://www.ncbi.nlm.nih.gov/pubmed/33563981 http://dx.doi.org/10.1038/s41467-021-21197-1

Ejemplares similares

Mobile elements contribute to the uniqueness of human genome with 15,000 human-specific insertions and 14 Mbp sequence increase
por: Tang, Wanxiangfu, et al.
Publicado: (2018)

Human Retrotransposons and Effective Computational Detection Methods for Next-Generation Sequencing Data
por: Lee, Haeun, et al.
Publicado: (2022)

Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition
por: Choi, Jongsu, et al.
Publicado: (2018)

Aicardi-Goutières syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription–replication conflict regions
por: Park, Kiwon, et al.
Publicado: (2021)

SAMHD1 specifically restricts retroviruses through its RNase activity
por: Choi, Jongsu, et al.
Publicado: (2015)

Novel Discovery of LINE-1 in a Korean Individual by a Target Enrichment Method
por: Shin, Wonseok, et al.
Publicado: (2019)

Pan-cancer analysis reveals multifaceted roles of retrotransposon-fusion RNAs
por: Lee, Boram, et al.
Publicado: (2023)

The Whole-Genome and Transcriptome of the Manila Clam (Ruditapes philippinarum)
por: Mun, Seyoung, et al.
Publicado: (2017)

The Time Sequence of Gene Expression Changes after Spinal Cord Injury
por: Mun, Seyoung, et al.
Publicado: (2022)

Role of the proline-rich disordered domain of DROSHA in intronic microRNA processing
por: Son, Soomin, et al.
Publicado: (2023)

Genome-wide methylation patterns predict clinical benefit of immunotherapy in lung cancer
por: Kim, Jeong Yeon, et al.
Publicado: (2020)

Whole-exome sequencing reveals rare genetic variations in ovarian granulosa cell tumor
por: Kim, Seungyeon, et al.
Publicado: (2022)

Comparative Analysis for Genetic Characterization in Korean Native Jeju Horse
por: Lee, Wooseok, et al.
Publicado: (2021)

Network perturbation by recurrent regulatory variants in cancer
por: Jang, Kiwon, et al.
Publicado: (2017)

Functional and molecular dissection of HCMV long non-coding RNAs
por: Lee, Sungwon, et al.
Publicado: (2022)

Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells
por: Ko, Eun-Ji, et al.
Publicado: (2021)

Diagnostic evaluation of qRT-PCR-based kit and dPCR-based kit for COVID-19
por: Lee, Cherl-Joon, et al.
Publicado: (2021)

Chromosomal Inversions between Human and Chimpanzee Lineages Caused by Retrotransposons
por: Lee, Jungnam, et al.
Publicado: (2008)

Identification of Potentially Pathogenic Variants Associated with Recurrence in Medication-Related Osteonecrosis of the Jaw (MRONJ) Patients Using Whole-Exome Sequencing
por: Kim, Songmi, et al.
Publicado: (2022)

Chimpanzee-Specific Endogenous Retrovirus Generates Genomic Variations in the Chimpanzee Genome
por: Mun, Seyoung, et al.
Publicado: (2014)

Rapid identification of SARS-CoV-2 in the point-of-care using digital PCR-based Dr. PCR™ Di20K COVID-19 Detection Kit without viral RNA extraction
por: Shin, Wonseok, et al.
Publicado: (2022)

Genome-Wide Pathway Exploration of the Epidermidibacterium keratini EPI-7(T)
por: Oh, Yunseok, et al.
Publicado: (2023)

Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers
por: Jung, Hyunchul, et al.
Publicado: (2018)

Comprehensive characterisation of intronic mis-splicing mutations in human cancers
por: Jung, Hyunchul, et al.
Publicado: (2021)

Transcriptional control and exploitation of an immune‐responsive family of plant retrotransposons
por: Zervudacki, Jérôme, et al.
Publicado: (2018)

Global transcription network incorporating distal regulator binding reveals selective cooperation of cancer drivers and risk genes
por: Kim, Kwoneel, et al.
Publicado: (2015)

A central role for PI3K-AKT signaling pathway in linking SAMHD1-deficiency to the type I interferon signature
por: Oh, Changhoon, et al.
Publicado: (2018)

Nourishing neonatal piglets with synthetic milk and Lactobacillus sp. at birth highly modifies the gut microbial communities at the post-weaning stage
por: Sampath, Vetriselvi, et al.
Publicado: (2022)

De novo identification of LTR retrotransposons in eukaryotic genomes
por: Rho, Mina, et al.
Publicado: (2007)

Amelogenic transcriptome profiling in ameloblast-like cells derived from adult gingival epithelial cells
por: Hyun, Sun-Yi, et al.
Publicado: (2019)

Past, Present, and Future of Brain Organoid Technology
por: Koo, Bonsang, et al.
Publicado: (2019)

Comparison of the oral microbial composition between healthy individuals and periodontitis patients in different oral sampling sites using 16S metagenome profiling
por: Kim, Yeon-Tae, et al.
Publicado: (2022)

The association between long working hours and hearing impairment in noise unexposed workers: data from the 5th Korea National Health and Nutrition Examination Survey (KNHANES 2010–2012)
por: Park, Jung-Woo, et al.
Publicado: (2016)

High Levels of Sequence Diversity in the 5′ UTRs of Human-Specific L1 Elements
por: Lee, Jungnam, et al.
Publicado: (2012)

Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle
por: Lee, Jea-young, et al.
Publicado: (2016)

Effects of Timely Control Intervention on the Spread of Middle East Respiratory Syndrome Coronavirus Infection
por: Choi, Ilsu, et al.
Publicado: (2017)

Predicting the recurrence of noncoding regulatory mutations in cancer
por: Yang, Woojin, et al.
Publicado: (2016)

The relationship between night work and involuntary weight change: data from the fifth Korea National Health and Nutrition Examination Survey (KNHANES 2010–2012)
por: Kwon, Jongho, et al.
Publicado: (2016)

A Note on Obesity as Epidemic in Korea
por: Kim, Mun Seok, et al.
Publicado: (2011)

Chicken (Gallus gallus) endogenous retrovirus generates genomic variations in the chicken genome
por: Lee, Jinmin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_r284fh72qd8n4cie6v3k60f3be