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Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs
A subset of CD4 + lymphocytes, regulatory T cells (Tregs), are necessary for central tolerance and function as suppressors of autoimmunity against self-antigens. The SRC-3 coactivator is an oncogene in multiple cancers and is capable of potentiating numerous transcription factors in a wide variety o...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873281/ https://www.ncbi.nlm.nih.gov/pubmed/33564037 http://dx.doi.org/10.1038/s41598-021-82945-3 |