Cargando…
Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs
A subset of CD4 + lymphocytes, regulatory T cells (Tregs), are necessary for central tolerance and function as suppressors of autoimmunity against self-antigens. The SRC-3 coactivator is an oncogene in multiple cancers and is capable of potentiating numerous transcription factors in a wide variety o...
Autores principales: | Nikolai, Bryan C., Jain, Prashi, Cardenas, David L., York, Brian, Feng, Qin, McKenna, Neil J., Dasgupta, Subhamoy, Lonard, David M., O’Malley, Bert W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873281/ https://www.ncbi.nlm.nih.gov/pubmed/33564037 http://dx.doi.org/10.1038/s41598-021-82945-3 |
Ejemplares similares
-
Tumor Suppressor Role for the SPOP Ubiquitin Ligase in Signal-Dependent Proteolysis of the Oncogenic Coactivator SRC-3/AIB1
por: Li, Chao, et al.
Publicado: (2011) -
Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug
por: Song, Xianzhou, et al.
Publicado: (2015) -
Steroid receptor coactivators – their role in immunity
por: Gilad, Yosi, et al.
Publicado: (2022) -
Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment
por: Han, Sang Jun, et al.
Publicado: (2022) -
Steroid receptor coactivator 3 is a key modulator of regulatory T cell–mediated tumor evasion
por: Han, Sang Jun, et al.
Publicado: (2023)