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Identification of epigenetic memory candidates associated with gestational age at birth through analysis of methylome and transcriptional data

Preterm birth is known to be associated with chronic disease risk in adulthood whereby epigenetic memory may play a mechanistic role in disease susceptibility. Gestational age (GA) is the most important prognostic factor for preterm infants, and numerous DNA methylation alterations associated with G...

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Detalles Bibliográficos
Autores principales: Kashima, Kohei, Kawai, Tomoko, Nishimura, Riki, Shiwa, Yuh, Urayama, Kevin Y., Kamura, Hiromi, Takeda, Kazue, Aoto, Saki, Ito, Atsushi, Matsubara, Keiko, Nagamatsu, Takeshi, Fujii, Tomoyuki, Omori, Isaku, Shimizu, Mitsumasa, Hyodo, Hironobu, Kugu, Koji, Matsumoto, Kenji, Shimizu, Atsushi, Oka, Akira, Mizuguchi, Masashi, Nakabayashi, Kazuhiko, Hata, Kenichiro, Takahashi, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873311/
https://www.ncbi.nlm.nih.gov/pubmed/33564054
http://dx.doi.org/10.1038/s41598-021-83016-3