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The Prognostic and Therapeutic Value of the Mutational Profile of Blood and Tumor Tissue in Head and Neck Squamous Cell Carcinoma

BACKGROUND: The purpose of this study was to explore the genomic landscape of head and neck squamous cell carcinoma (HNSCC) in circulation (circulating tumor DNA [ctDNA]) and tumor (tumor tissue DNA [tDNA]) and understand the implications of ctDNA sequencing for prognosis and precision oncology trea...

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Detalles Bibliográficos
Autores principales: Wilson, Harper L., D'Agostino, Ralph B., Meegalla, Nuwan, Petro, Robin, Commander, Sara, Topaloglu, Umit, Zhang, Wei, Porosnicu, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873320/
https://www.ncbi.nlm.nih.gov/pubmed/33098199
http://dx.doi.org/10.1002/onco.13573