Cardiomyocyte Na(+)/H(+) Exchanger-1 Activity Is Reduced in Hypoxia

Fully-activated Na(+)/H(+) exchanger-1 (NHE1) generates the cardiomyocyte's largest trans-membrane extrusion of H(+) ions for an equimolar influx of Na(+) ions. This has the desirable effect of clearing excess intracellular acidity, but comes at a large energetic premium because the exchanged N...

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Detalles Bibliográficos
Autores principales: Kandilci, Hilmi Burak, Richards, Mark A., Fournier, Marjorie, Şimşek, Gül, Chung, Yu Jin, Lakhal-Littleton, Samira, Swietach, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873356/
https://www.ncbi.nlm.nih.gov/pubmed/33585583
http://dx.doi.org/10.3389/fcvm.2020.617038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873356/
https://www.ncbi.nlm.nih.gov/pubmed/33585583
http://dx.doi.org/10.3389/fcvm.2020.617038

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