Cynandione A Alleviates Neuropathic Pain Through α7-nAChR-Dependent IL-10/β-Endorphin Signaling Complexes

Cynandione A, an acetophenone isolated from Cynanchum Wilfordii Radix, exhibits antineuropathic pain effect. This study further explored the target molecule and signaling mechanisms underlying cynandione-A-induced antineuropathic pain. Intrathecal injection of cynandione A significantly attenuated m...

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Detalles Bibliográficos
Autores principales: Han, Qiao-Qiao, Yin, Min, Wang, Zi-Ying, Liu, Hao, Ao, Jun-Ping, Wang, Yong-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873367/
https://www.ncbi.nlm.nih.gov/pubmed/33584292
http://dx.doi.org/10.3389/fphar.2020.614450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873367/
https://www.ncbi.nlm.nih.gov/pubmed/33584292
http://dx.doi.org/10.3389/fphar.2020.614450

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