Inactivation of the PD-1-Dependent Immunoregulation in Mice Exacerbates Contact Hypersensitivity Resembling Immune-Related Adverse Events

Blockade of PD-1, an indispensable physiological immunoregulatory mechanism, enhances immune activities and is widely used in the immunotherapy of cancer. This treatment often accompanies inflammatory complication called immune-related adverse events (irAE), most frequently in the skin. To analyze h...

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Detalles Bibliográficos
Autores principales: Ashoori, Matin Dokht, Suzuki, Kensuke, Tokumaru, Yosuke, Ikuta, Naoko, Tajima, Masaki, Honjo, Tasuku, Ohta, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873368/
https://www.ncbi.nlm.nih.gov/pubmed/33584713
http://dx.doi.org/10.3389/fimmu.2020.618711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873368/
https://www.ncbi.nlm.nih.gov/pubmed/33584713
http://dx.doi.org/10.3389/fimmu.2020.618711

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