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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

OBJECTIVE: Maintenance of glucose homeostasis requires the precise regulation of hormone secretion from the endocrine pancreas. Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor whose activation in islets of Langerhans promotes insulin and glucagon secretion and inhibits soma...

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Detalles Bibliográficos
Autores principales: Croze, Marine L., Flisher, Marcus F., Guillaume, Arthur, Tremblay, Caroline, Noguchi, Glyn M., Granziera, Sabrina, Vivot, Kevin, Castillo, Vincent C., Campbell, Scott A., Ghislain, Julien, Huising, Mark O., Poitout, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873385/
https://www.ncbi.nlm.nih.gov/pubmed/33484949
http://dx.doi.org/10.1016/j.molmet.2021.101166