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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
OBJECTIVE: Maintenance of glucose homeostasis requires the precise regulation of hormone secretion from the endocrine pancreas. Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor whose activation in islets of Langerhans promotes insulin and glucagon secretion and inhibits soma...
Autores principales: | Croze, Marine L., Flisher, Marcus F., Guillaume, Arthur, Tremblay, Caroline, Noguchi, Glyn M., Granziera, Sabrina, Vivot, Kevin, Castillo, Vincent C., Campbell, Scott A., Ghislain, Julien, Huising, Mark O., Poitout, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873385/ https://www.ncbi.nlm.nih.gov/pubmed/33484949 http://dx.doi.org/10.1016/j.molmet.2021.101166 |
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