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Emerging Technologies for Genome-Wide Profiling of DNA Breakage

Genome instability is associated with myriad human diseases and is a well-known feature of both cancer and neurodegenerative disease. Until recently, the ability to assess DNA damage—the principal driver of genome instability—was limited to relatively imprecise methods or restricted to studying pred...

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Detalles Bibliográficos
Autores principales: Rybin, Matthew J., Ramic, Melina, Ricciardi, Natalie R., Kapranov, Philipp, Wahlestedt, Claes, Zeier, Zane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873462/
https://www.ncbi.nlm.nih.gov/pubmed/33584810
http://dx.doi.org/10.3389/fgene.2020.610386