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A new class of α-ketoamide derivatives with potent anticancer and anti-SARS-CoV-2 activities

Inhibitors of the proteasome have been extensively studied for their applications in the treatment of human diseases such as hematologic malignancies, autoimmune disorders, and viral infections. Many of the proteasome inhibitors reported in the literature target the non-primed site of proteasome’s s...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Liang, Boqiang, Chen, Yiling, Fuk-Woo Chan, Jasper, Yuan, Shuofeng, Ye, Hui, Nie, Linlin, Zhou, Jiao, Wu, Yi, Wu, Meixian, Huang, Lina S., An, Jing, Warshel, Arieh, Yuen, Kwok-Yung, Ciechanover, Aaron, Huang, Ziwei, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873610/
https://www.ncbi.nlm.nih.gov/pubmed/33639344
http://dx.doi.org/10.1016/j.ejmech.2021.113267