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Global proteomics of Ubqln2-based murine models of ALS

Familial neurodegenerative diseases commonly involve mutations that result in either aberrant proteins or dysfunctional components of the proteolytic machinery that act on aberrant proteins. UBQLN2 is a ubiquitin receptor of the UBL/UBA family that binds the proteasome through its ubiquitin-like dom...

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Detalles Bibliográficos
Autores principales: Whiteley, Alexandra M., Prado, Miguel A., de Poot, Stefanie A.H., Paulo, Joao A., Ashton, Marissa, Dominguez, Sara, Weber, Martin, Ngu, Hai, Szpyt, John, Jedrychowski, Mark P., Easton, Amy, Gygi, Steven P., Kurz, Thimo, Monteiro, Mervyn J., Brown, Eric J., Finley, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873701/
https://www.ncbi.nlm.nih.gov/pubmed/33277362
http://dx.doi.org/10.1074/jbc.RA120.015960