The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers

Glucocorticoids (GCs) are effective anti-inflammatory drugs; yet, their mechanisms of action are poorly understood. GCs bind to the glucocorticoid receptor (GR), a ligand-gated transcription factor controlling gene expression in numerous cell types. Here, we characterize GR’s protein interactome and...

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Detalles Bibliográficos
Autores principales: Greulich, Franziska, Wierer, Michael, Mechtidou, Aikaterini, Gonzalez-Garcia, Omar, Uhlenhaut, N. Henriette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873837/
https://www.ncbi.nlm.nih.gov/pubmed/33567280
http://dx.doi.org/10.1016/j.celrep.2021.108742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873837/
https://www.ncbi.nlm.nih.gov/pubmed/33567280
http://dx.doi.org/10.1016/j.celrep.2021.108742

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