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Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity

Aristolactam I (ALI) is an active component derived from some Traditional Chinese medicines (TCMs), and also the important metabolite of aristolochic acid. Long-term administration of medicine-containing ALI was reported to be related to aristolochic acid nephropathy (AAN), which was attributed to A...

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Detalles Bibliográficos
Autores principales: Deng, Hui-Fang, Yue, Lan-Xin, Wang, Ning-Ning, Zhou, Yong-Qiang, Zhou, Wei, Liu, Xian, Ni, Yu-Hao, Huang, Cong-Shu, Qiu, Li-Zhen, Liu, Hong, Tan, Hong-Ling, Tang, Xiang-Lin, Wang, Yu-Guang, Ma, Zeng-Chun, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873870/
https://www.ncbi.nlm.nih.gov/pubmed/33584308
http://dx.doi.org/10.3389/fphar.2020.624529