Decitabine Induces Change of Biological Traits in Myelodysplastic Syndromes via FOXO1 Activation

Decitabine (DAC) is considered to be a profound global DNA demethylation, which can induce the re-expression of silenced tumor suppressor genes. Little is known about the function of tumor suppressor gene FOXO1 in myelodysplastic syndromes (MDS). To address this issue, the study firstly investigated...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Jia, Yan, Xv, Feng, Song, Lu-xi, Shi, Lei, Guo, Juan, Chang, Chun-kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873873/
https://www.ncbi.nlm.nih.gov/pubmed/33584800
http://dx.doi.org/10.3389/fgene.2020.603956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873873/
https://www.ncbi.nlm.nih.gov/pubmed/33584800
http://dx.doi.org/10.3389/fgene.2020.603956

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