Cargando…
Decitabine Induces Change of Biological Traits in Myelodysplastic Syndromes via FOXO1 Activation
Decitabine (DAC) is considered to be a profound global DNA demethylation, which can induce the re-expression of silenced tumor suppressor genes. Little is known about the function of tumor suppressor gene FOXO1 in myelodysplastic syndromes (MDS). To address this issue, the study firstly investigated...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873873/ https://www.ncbi.nlm.nih.gov/pubmed/33584800 http://dx.doi.org/10.3389/fgene.2020.603956 |