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VLA-1 Binding to Collagen IV Controls Effector T Cell Suppression by Myeloid-Derived Suppressor Cells in the Splenic Red Pulp

Myeloid-derived suppressor cells (MDSCs) represent a major population controlling T cell immune responses. However, little is known about their molecular requirements for homing and T cell interaction to mediate suppression. Here, we investigated the functional role of the homing and collagen IV rec...

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Detalles Bibliográficos
Autores principales: Eckert, Ina N., Ribechini, Eliana, Jarick, Katja J., Strozniak, Sandra, Potter, Sarah J., Beilhack, Andreas, Lutz, Manfred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873891/
https://www.ncbi.nlm.nih.gov/pubmed/33584706
http://dx.doi.org/10.3389/fimmu.2020.616531