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Activity of Tracheal Cytotoxin of Bordetella pertussis in a Human Tracheobronchial 3D Tissue Model

Bordetella pertussis is a highly contagious pathogen which causes whooping cough in humans. A major pathophysiology of infection is the extrusion of ciliated cells and subsequent disruption of the respiratory mucosa. Tracheal cytotoxin (TCT) is the only virulence factor produced by B. pertussis that...

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Detalles Bibliográficos
Autores principales: Kessie, David K., Lodes, Nina, Oberwinkler, Heike, Goldman, William E., Walles, Thorsten, Steinke, Maria, Gross, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873972/
https://www.ncbi.nlm.nih.gov/pubmed/33585281
http://dx.doi.org/10.3389/fcimb.2020.614994