Development and Application of a Water Temperature Related Physiologically Based Pharmacokinetic Model for Enrofloxacin and Its Metabolite Ciprofloxacin in Rainbow Trout

Enrofloxacin (ENR) has been approved for the treatment of infections in aquaculture, but it may cause tissue residue. This research aimed to develop and validate a water temperature related PBPK model, including both ENR and ciprofloxacin (CIP), in rainbow trout, and to predict further their residue...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Yang, Fang, Wang, Dan, Zhang, Chao-Shuo, Wang, Han, Song, Zhe-Wen, Shao, Hao-Tian, Zhang, Mei, Yu, Meng-Li, Zheng, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874017/
https://www.ncbi.nlm.nih.gov/pubmed/33585600
http://dx.doi.org/10.3389/fvets.2020.608348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874017/
https://www.ncbi.nlm.nih.gov/pubmed/33585600
http://dx.doi.org/10.3389/fvets.2020.608348

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