Cargando…

SPARC Knockdown Reduces Glutamate-Induced HT22 Hippocampal Nerve Cell Damage by Regulating Autophagy

Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein involved in the extracellular matrix and interactions between cells during neural development of the central nervous system (CNS). Oxidative glutamate toxicity is involved in CNS diseases, including epilepsy, Alzheimer’s...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Shuang, Zou, Qin, Guo, Qiang, Chen, Yongmin, Kuang, Xi, Zhang, Yukang, Liu, Yan, Wu, Wengang, Li, Ge, Tu, Linzhi, Tong, Jingyi, Li, Songrong, Ma, Lin, Li, Qifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874057/
https://www.ncbi.nlm.nih.gov/pubmed/33584170
http://dx.doi.org/10.3389/fnins.2020.581441