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DAGLα Inhibition as a Non-invasive and Translational Model of Episodic Headache

Recent findings suggested that Clinical Endocannabinoid Deficiency underlies the pathophysiology of pain disorders, including migraine and headache. In models of medication overuse headache induced by sustained administration of sumatriptan or morphine, 2-AG levels were selectively depleted in the p...

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Detalles Bibliográficos
Autores principales: Levine, Aidan, Liktor-Busa, Erika, Karlage, Kelly L., Giancotti, Luigi, Salvemini, Daniela, Vanderah, Todd W., Largent-Milnes, Tally M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874129/
https://www.ncbi.nlm.nih.gov/pubmed/33584293
http://dx.doi.org/10.3389/fphar.2020.615028