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α-ketoglutarate promotes the specialization of primordial germ cell-like cells through regulating epigenetic reprogramming
There is growing evidence that cellular metabolism can directly participate in epigenetic dynamics and consequently modulate gene expression. However, the role of metabolites in activating the key gene regulatory network for specialization of germ cell lineage remains largely unknown. Here, we ident...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874270/ https://www.ncbi.nlm.nih.gov/pubmed/32994387 http://dx.doi.org/10.7555/JBR.34.20190160 |