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Prognostic and clinicopathological significance of hypoxia-inducible factors 1α and 2α in hepatocellular carcinoma: a systematic review with meta-analysis

BACKGROUND: Hepatocellular carcinoma (HCC) is a highly recurrent tumor after resection and has been closely related to hypoxia. Hypoxia-inducible factors 1α and 2α (HIF-1α and HIF-2α) have been shown to contribute to tumor progression and therapy resistance in HCC. We evaluated the prognostic and cl...

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Detalles Bibliográficos
Autores principales: Méndez-Blanco, Carolina, Fernández-Palanca, Paula, Fondevila, Flavia, González-Gallego, Javier, Mauriz, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874357/
https://www.ncbi.nlm.nih.gov/pubmed/33613697
http://dx.doi.org/10.1177/1758835920987071