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Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose

BACKGROUND: Gestational diabetes mellitus is a risk factor for congenital heart defects. The article aimed to investigate the expression and roles of MST1, YAP1, Last1/2 and Survivin in modulating HG-induced cardiomyocyte apoptosis and maternal diabetes-induced heart abnormality. METHODS: Diabetes m...

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Detalles Bibliográficos
Autores principales: Su, Dongmei, Li, Yanhua, Guan, Lina, Li, Qian, Shi, Cuige, Ma, Xu, Song, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874454/
https://www.ncbi.nlm.nih.gov/pubmed/33568044
http://dx.doi.org/10.1186/s10020-021-00267-6