Upregulated UCA1 contributes to oxaliplatin resistance of hepatocellular carcinoma through inhibition of miR‐138‐5p and activation of AKT/mTOR signaling pathway

Hepatocellular carcinoma (HCC) inevitably developed oxaliplatin (OXA) resistance after long‐term treatment, but the mechanism remains unclear. Here, we found that LncRNA UCA1 was upregulated in most of OXA‐resistant HCC tissues and cells (HepG2/OXA and SMMC‐7721/OXA). Follow‐up analysis and online K...

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Detalles Bibliográficos
Autores principales: Huang, Guolin, Li, Li, Liang, Chaoyong, Yu, Fei, Teng, Cuifang, Pang, Yingxing, Wei, Tongtong, Song, Jinjing, Wang, Hanlin, Liao, Xiaoli, Li, Yongqiang, Yang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874507/
https://www.ncbi.nlm.nih.gov/pubmed/33565716
http://dx.doi.org/10.1002/prp2.720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874507/
https://www.ncbi.nlm.nih.gov/pubmed/33565716
http://dx.doi.org/10.1002/prp2.720

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