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BRCA1 subcellular localization regulated by PI3K signaling pathway in triple-negative breast cancer MDA-MB-231 cells and hormone-sensitive T47D cells

This study is to investigate the effect of the PI3K/Akt signaling pathway on the regulation of BRCA1 subcellular localization in triple-negative breast cancer (TNBC) MDA-MB-231 cells and hormone-sensitive T47D cells. We found that heregulin-activated T47D cells showed more nuclear localization of BR...

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Detalles Bibliográficos
Autores principales: Ma, Bin, Guo, Wenjia, Shan, Meihui, Zhang, Nan, Ma, Binlin, Sun, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874579/
https://www.ncbi.nlm.nih.gov/pubmed/33817238
http://dx.doi.org/10.1515/biol-2020-0054