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Propofol suppresses cell viability, cell cycle progression and motility and induces cell apoptosis of ovarian cancer cells through suppressing MEK/ERK signaling via targeting circVPS13C/miR-145 axis

BACKGROUND: Propofol is a kind of common intravenous anaesthetic agent that plays an anti-tumor role in a variety of cancers, including ovarian cancer. However, the working mechanism of Propofol in ovarian cancer needs further exploration. METHODS: The viability and metastasis of ovarian cancer cell...

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Detalles Bibliográficos
Autores principales: Lu, Huan, Zheng, Guanlin, Gao, Xiang, Chen, Chanjuan, Zhou, Min, Zhang, Longxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874627/
https://www.ncbi.nlm.nih.gov/pubmed/33563314
http://dx.doi.org/10.1186/s13048-021-00775-3