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Edaravone Exerts Brain Protective Function by Reducing the Expression of AQP4, APP and Aβ Proteins

This study aims to investigate the changes of aquaporin-4 (AQP4), β-amyloid precursor proteins (APP) and β-amyloid (Aβ) in brain tissues after cerebral ischemiareperfusion injury (CIRI), and evaluate the effect of edaravone. The Middle Cerebral Artery Occlusion was used to establish CIRI in rats. Ra...

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Detalles Bibliográficos
Autores principales: Ren, Haiyan, Ma, Lijuan, Gong, Xueli, Xu, Chenbo, Zhang, Yuge, Ma, Meilei, Watanabe, Kenichi, Wen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874750/
https://www.ncbi.nlm.nih.gov/pubmed/33817204
http://dx.doi.org/10.1515/biol-2019-0074