IGF-1 Via PI3K/Akt/S6K Signaling Pathway Protects DRG Neurons with High Glucose-induced Toxicity

Hyperglycemia-induced toxicity of neurons contributes to the pathogenesis and progression of diabetic neuropathy (DNP). High concentration glucose triggered reactive oxygen species (ROS) overproduction and induced cell apoptosis of neurons from dorsal root ganglion (DRG) in vitro. Currently, there i...

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Detalles Bibliográficos
Autores principales: Liu, Chunhong, Liu, Siyan, Wang, Sheng, Sun, Yi, Lu, Xin, Li, Hao, Li, Guibao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874800/
https://www.ncbi.nlm.nih.gov/pubmed/33817186
http://dx.doi.org/10.1515/biol-2019-0056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874800/
https://www.ncbi.nlm.nih.gov/pubmed/33817186
http://dx.doi.org/10.1515/biol-2019-0056

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