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IGF-1 Via PI3K/Akt/S6K Signaling Pathway Protects DRG Neurons with High Glucose-induced Toxicity
Hyperglycemia-induced toxicity of neurons contributes to the pathogenesis and progression of diabetic neuropathy (DNP). High concentration glucose triggered reactive oxygen species (ROS) overproduction and induced cell apoptosis of neurons from dorsal root ganglion (DRG) in vitro. Currently, there i...
Autores principales: | Liu, Chunhong, Liu, Siyan, Wang, Sheng, Sun, Yi, Lu, Xin, Li, Hao, Li, Guibao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874800/ https://www.ncbi.nlm.nih.gov/pubmed/33817186 http://dx.doi.org/10.1515/biol-2019-0056 |
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