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Ethanol Disrupts Hormone-Induced Calcium Signaling in Liver

Receptor-coupled phospholipase C (PLC) is an important target for the actions of ethanol. In the ex vivo perfused rat liver, concentrations of ethanol >100 mM were required to induce a rise in cytosolic calcium (Ca(2+)) suggesting that these responses may only occur after binge ethanol consumptio...

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Detalles Bibliográficos
Autores principales: Gaspers, Lawrence D, Thomas, Andrew P, Hoek, Jan B, Bartlett, Paula J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875097/
https://www.ncbi.nlm.nih.gov/pubmed/33604575
http://dx.doi.org/10.1093/function/zqab002