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Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate

Cell fate transitions are frequently accompanied by changes in cell shape and mechanics. However, how cellular mechanics affects the instructive signaling pathways controlling cell fate is poorly understood. To probe the interplay between shape, mechanics, and fate, we use mouse embryonic stem cells...

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Detalles Bibliográficos
Autores principales: De Belly, Henry, Stubb, Aki, Yanagida, Ayaka, Labouesse, Céline, Jones, Philip H., Paluch, Ewa K., Chalut, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875115/
https://www.ncbi.nlm.nih.gov/pubmed/33217323
http://dx.doi.org/10.1016/j.stem.2020.10.018