Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity

In response to physical exercise and diet, skeletal muscle adapts to energetic demands through large transcriptional changes. This remodelling is associated with changes in skeletal muscle DNA methylation which may participate in the metabolic adaptation to extracellular stimuli. Yet, the mechanisms...

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Detalles Bibliográficos
Autores principales: Small, Lewin, Ingerslev, Lars R., Manitta, Eleonora, Laker, Rhianna C., Hansen, Ann N., Deeney, Brendan, Carrié, Alain, Couvert, Philippe, Barrès, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875352/
https://www.ncbi.nlm.nih.gov/pubmed/33513138
http://dx.doi.org/10.1371/journal.pgen.1009325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875352/
https://www.ncbi.nlm.nih.gov/pubmed/33513138
http://dx.doi.org/10.1371/journal.pgen.1009325

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