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Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity
In response to physical exercise and diet, skeletal muscle adapts to energetic demands through large transcriptional changes. This remodelling is associated with changes in skeletal muscle DNA methylation which may participate in the metabolic adaptation to extracellular stimuli. Yet, the mechanisms...
Autores principales: | Small, Lewin, Ingerslev, Lars R., Manitta, Eleonora, Laker, Rhianna C., Hansen, Ann N., Deeney, Brendan, Carrié, Alain, Couvert, Philippe, Barrès, Romain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875352/ https://www.ncbi.nlm.nih.gov/pubmed/33513138 http://dx.doi.org/10.1371/journal.pgen.1009325 |
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