Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

Neonatal echovirus infections are characterized by severe hepatitis and neurological complications that can be fatal. Here, we show that expression of the human homologue of the neonatal Fc receptor (hFcRn), the primary receptor for echoviruses, and ablation of type I interferon (IFN) signaling are...

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Detalles Bibliográficos
Autores principales: Wells, Alexandra I., Grimes, Kalena A., Kim, Kenneth, Branche, Emilie, Bakkenist, Christopher J., DePas, William H., Shresta, Sujan, Coyne, Carolyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875378/
https://www.ncbi.nlm.nih.gov/pubmed/33513208
http://dx.doi.org/10.1371/journal.ppat.1009252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875378/
https://www.ncbi.nlm.nih.gov/pubmed/33513208
http://dx.doi.org/10.1371/journal.ppat.1009252

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