MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen

Androgen deprivation therapy (ADT) is a mainstay of prostate cancer treatment, given the dependence of prostate cells on androgen and the androgen receptor (AR). However, tumors become ADT-resistant, and there is a need to understand the mechanism. One possible mechanism is the upregulation of AR co...

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Detalles Bibliográficos
Autores principales: Weber, Hannah, Ruoff, Rachel, Garabedian, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875385/
https://www.ncbi.nlm.nih.gov/pubmed/33513133
http://dx.doi.org/10.1371/journal.pgen.1008540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875385/
https://www.ncbi.nlm.nih.gov/pubmed/33513133
http://dx.doi.org/10.1371/journal.pgen.1008540

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