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A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

Type 1 pili have long been considered the major virulence factor enabling colonization of the urinary bladder by uropathogenic Escherichia coli (UPEC). The molecular pathogenesis of pyelonephritis is less well characterized, due to previous limitations in preclinical modeling of kidney infection. He...

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Detalles Bibliográficos
Autores principales: McLellan, Lisa K., McAllaster, Michael R., Kim, Arthur S., Tóthová, Ľubomíra, Olson, Patrick D., Pinkner, Jerome S., Daugherty, Allyssa L., Hreha, Teri N., Janetka, James W., Fremont, Daved H., Hultgren, Scott J., Virgin, Herbert W., Hunstad, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875428/
https://www.ncbi.nlm.nih.gov/pubmed/33513212
http://dx.doi.org/10.1371/journal.ppat.1009314