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A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis
Type 1 pili have long been considered the major virulence factor enabling colonization of the urinary bladder by uropathogenic Escherichia coli (UPEC). The molecular pathogenesis of pyelonephritis is less well characterized, due to previous limitations in preclinical modeling of kidney infection. He...
Autores principales: | McLellan, Lisa K., McAllaster, Michael R., Kim, Arthur S., Tóthová, Ľubomíra, Olson, Patrick D., Pinkner, Jerome S., Daugherty, Allyssa L., Hreha, Teri N., Janetka, James W., Fremont, Daved H., Hultgren, Scott J., Virgin, Herbert W., Hunstad, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875428/ https://www.ncbi.nlm.nih.gov/pubmed/33513212 http://dx.doi.org/10.1371/journal.ppat.1009314 |
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