AIRE deficiency, from preclinical models to human APECED disease

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare life-threatening autoimmune disease that attacks multiple organs and has its onset in childhood. It is an inherited condition caused by a variety of mutations in the autoimmune regulator (AIRE) gene that encodes a prot...

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Detalles Bibliográficos
Autores principales: Besnard, Marine, Padonou, Francine, Provin, Nathan, Giraud, Matthieu, Guillonneau, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875492/
https://www.ncbi.nlm.nih.gov/pubmed/33729987
http://dx.doi.org/10.1242/dmm.046359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875492/
https://www.ncbi.nlm.nih.gov/pubmed/33729987
http://dx.doi.org/10.1242/dmm.046359

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