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A General Protocol for Cu-Mediated Fluoro-deamination: Sandmeyer Fluorination of Diverse Aromatic Substrates

[Image: see text] A Cu(I)-mediated fluoro-deamination method for nucleophilic radiofluorination was devised. The method affords fluorinated aromatic products directly from anilines under both no-carrier added and stoichiometric conditions. Isolated radiochemical yields range from 11% to 81% with hig...

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Detalles Bibliográficos
Autores principales: Pérez-García, R. Manuel, Grønnevik, Gaute, Riss, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875512/
https://www.ncbi.nlm.nih.gov/pubmed/33492972
http://dx.doi.org/10.1021/acs.orglett.0c04209