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Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization and in vivo evaluation

Voriconazole (VCZ) is a well-known broad spectrum triazole antifungal, mainly used orally and intravenously. The study aimed to formulate VCZ into ultradeformable elastosomes for the topical treatment of ocular fungal keratitis. Different formulae were prepared using a modified ethanol injection met...

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Detalles Bibliográficos
Autores principales: Fahmy, Abdurrahman Muhammad, Hassan, Mariam, El-Setouhy, Doaa Ahmed, Tayel, Saadia Ahmed, Al-Mahallawi, Abdulaziz Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875553/
https://www.ncbi.nlm.nih.gov/pubmed/33342315
http://dx.doi.org/10.1080/10717544.2020.1858997