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Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization and in vivo evaluation
Voriconazole (VCZ) is a well-known broad spectrum triazole antifungal, mainly used orally and intravenously. The study aimed to formulate VCZ into ultradeformable elastosomes for the topical treatment of ocular fungal keratitis. Different formulae were prepared using a modified ethanol injection met...
Autores principales: | Fahmy, Abdurrahman Muhammad, Hassan, Mariam, El-Setouhy, Doaa Ahmed, Tayel, Saadia Ahmed, Al-Mahallawi, Abdulaziz Mohsen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875553/ https://www.ncbi.nlm.nih.gov/pubmed/33342315 http://dx.doi.org/10.1080/10717544.2020.1858997 |
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