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Exenatide-loaded inside-porous poly(lactic-co-glycolic acid) microspheres as a long-acting drug delivery system with improved release characteristics

The glucagon-like peptide-1 receptor agonist exenatide (EXT) is an effective treatment for type 2 diabetes. However, this peptide has a short biological half-life and the delayed release characteristic of current formulations limit its clinical application. Herein, we prepared EXT-loaded inside-poro...

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Detalles Bibliográficos
Autores principales: Zhai, Junqiu, Ou, Zhanlun, Zhong, Liuting, Wang, Yu-e, Cao, Li-Ping, Guan, Shixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875555/
https://www.ncbi.nlm.nih.gov/pubmed/33241694
http://dx.doi.org/10.1080/10717544.2020.1850919